Prednisone cured my fatigue, but why did it turn me into the Energizer Bunny?

Published: July 23, 2012

Dear Dr. T,

Long story short. I was eventually perscribed prednisone 20 mg for two weeks. After the 3rd day it helped the reaction I was having. What I noticed more so was that the pain and fatique was gone! My head was clear. I figured it was the med and knew it was a hard drug on the body, but I took advantage of it and was like the energizer bunny, cleaned, rearranged and finished UFO's,(unfinished objects). With winter coming I knew I would be down for the season, and wanted everything in order before this happened. Ok, so story not so short. What is in the prednisone that made me feel so good? I wish the side effects weren't so bad on the body :-(



Dear Sharon,

We talk alot about adrenal fatigue and the prednisone is treating this. The bad news? 20 mg a day of prednisone would get pretty toxic with extended use (usually months — not weeks). The good news? Most people need nowhere near that dose to get optimal benefits for adrenal support, and the cortef 20 mg a day (like 4 mg/d of prednisone) has been safely used long term — and you may even need a lower dose. Don't expect to get the "energizer bunny" stimulant effect (fun for a while but not healthy long term), but rather to feel healthy energy. If the lower dose does not work, then the prednisone may have been acting as an anti-inflammatory. So your doctor may want to check a sed rate blood test (when NOT on the prednisone) and look for causes of the inflammation (e.g., autoimmune disease and infections).


Dr. T


Jacob Teitelbaum, MD

is one of the world's leading integrative medical authorities on fibromyalgia and chronic fatigue. He is the lead author of eight research studies on their effective treatments, and has published numerous health & wellness books, including the bestseller on fibromyalgia From Fatigued to Fantastic! and The Fatigue and Fibromyalgia Solution. His newest book (June 10, 2024) is You Can Heal From Long COVID. Dr. Teitelbaum is one of the most frequently quoted fibromyalgia experts in the world and appears often as a guest on news and talk shows nationwide including Good Morning America, The Dr. Oz Show, Oprah & Friends, CNN, and Fox News Health.

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