Whats is the difference between Neurontin and Lyrica for pain?

Published: February 21, 2014

What is the difference between Neurontin and Lyrica for pain? Is it true that Neurontin increases GABA? Does Lyrica increase GABA? Is Neurontin just as good a Lyrica?


Both are related meds that are chemical similar to GABA and work through what are called sodium channels. Though related, one may work where the other does not. i usually begin with the neurontin (effective, less side effects and much lower cost) and Ultram, moving to Lyrica or Cymbalta if these don't work.

Dr. T

Jacob Teitelbaum, MD

is one of the world's leading integrative medical authorities on fibromyalgia and chronic fatigue. He is the lead author of eight research studies on their effective treatments, and has published numerous health & wellness books, including the bestseller on fibromyalgia From Fatigued to Fantastic! and The Fatigue and Fibromyalgia Solution. His newest book (June 10, 2024) is You Can Heal From Long COVID. Dr. Teitelbaum is one of the most frequently quoted fibromyalgia experts in the world and appears often as a guest on news and talk shows nationwide including Good Morning America, The Dr. Oz Show, Oprah & Friends, CNN, and Fox News Health.

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